For researchers · Scientific programme

The next question starts with measured response.

AiMediq continues an established ReOxy-specific clinical research programme on individually dosed IHHT®.

Develop the next research question, protocol and outcome measures with us.

We welcome research partners.

The programme at a glance

Focus for discussion Cardiac rehabilitation in stable ischaemic heart disease
Further research questions Discussed in scientific exchange Detailed programme for healthcare professionals and researchers

Detailed research questions, study populations and limitations are presented in the professional research programme. Research areas are not additional device indications.

01

The programme

A research programme built with partners

Research questions, endpoints and study design are developed together with research partners. We are looking for clinical and academic groups with experience in cardiac rehabilitation and clinical research.

The programme is open to principal investigators in hospitals and university clinics, physician-scientists and research groups without a clinical practice.

Who we would like to hear from

  • Cardiology and cardiac rehabilitation research groups
  • Principal investigators planning investigator-initiated studies
  • Physiologists working with exercise testing and patient monitoring
  • Centres interested in multicentre collaboration

These are prospective collaborators invited to discuss a project; the list does not claim that any institution is a committed partner.

02

Technology for study protocols

What ReOxy® measures and how exposure is guided

Measured signals

ReOxy continuously measures SpO₂ and pulse rate using Masimo SET® pulse oximetry and displays perfusion index. The supplied-gas flow trace represents breathing pattern.

ReOxy® implements ICU/CCU-grade SpO₂ monitoring integrated into the measurement and control architecture.

  • SpO₂
  • Pulse rate
  • Perfusion index
  • Breathing pattern

Response-guided dosing

SRT® Technology uses the measured physiological response to guide hypoxic exposure and hyperoxic recovery throughout the treatment.

AiMediq has developed the IHHT® method since 2005 (first patent filings in 2005 and 2008). Response-guided exposure and recovery are described in European patent EP 3 452 154 B1.

How dosing works

Research specifications

Signal list, sampling, data export and the options for a control condition — as a technical sheet for study protocols, on request.

PDF test, treatment and course reports and detailed procedure data in CSV can be exported via USB. The IFU also describes technical raw-data export for manufacturer analysis; this is distinct from general research access. Study-specific control-condition hardware and access to technical data are specified for each project.

Ask for research specifications

Intended use of ReOxy®

Intended use: improvement of physical exercise capacity in adult and senior patients with coronary artery disease (CAD).

For use in a clinical environment under professional supervision and according to a doctor's prescription.

Studies outside the intended use follow their own regulatory pathway, which we clarify with each research partner.

03

How we collaborate

From a first conversation to a joint study

  1. 01

    Start a scientific conversation

    Tell us about your group, your research question and your setting. Your request goes to our medical and scientific team.

  2. 02

    Scientific discussion

    We discuss the question, the published studies and the measurements available with ReOxy®. Healthcare professionals and researchers can request the relevant publications and discuss access to further materials with our medical team.

  3. 03

    Joint study design

    Protocol, endpoints, control condition, sample size, participating centres and funding are agreed together.

  4. 04

    Approvals and set-up

    Ethics approval, contracts, device provision and operator training for the study team.

    Device provision, training, funding, data access and responsibilities are specified in the study agreement for each project.

  5. 05

    Conduct and publication

    The publication plan, investigator roles, disclosure of support and handling of confidential information are agreed before the study starts.

04

Publications

Published studies and the scientific library

Published studies with ReOxy® are available to healthcare professionals and researchers on request from our medical team.

For healthcare professionals and researchers

Scientific library

Request publications with their full references, study designs and limitations, or discuss a specific research question with our team. Professional access to further materials follows the applicable country and audience requirements.

05

Contact the medical and scientific team

Bring a question. Build the next study.

Tell us your research question, institution and the materials you need. We can then discuss the appropriate scientific contact and next step.

Medical and scientific team
[email protected]
Next step
A discussion of your research question and the relevant source material.

Requests from distribution partners and clinics about purchasing: Contact.

Your research proposal

This form is for healthcare professionals, healthcare institutions, research and business partners. If you are a patient or a relative, please talk to your doctor. Please do not send medical information.

An institutional address helps us verify research access.
Setting of the planned study
A few sentences are enough. Please do not send medical information.

To report a side effect, an incident or a complaint related to ReOxy®, please write to [email protected].

Data protection

Data protection: Ai Mediq S.A., 19, rue de Bitbourg, L-1273 Luxembourg, processes the information you provide to handle your enquiry. Please do not include patient data or other health information. For questions about personal data, contact [email protected]. Read the privacy notice.